Product Description of Ademetionine Disulfate Tosylate CAS#97540-22-2
Ademetionine disulfate tosylate is a stable mixed-salt compound formed by two sulfate anions and one tosylate anion with ademetionine diastereoisomers. It appears as white to off-white crystalline powder, featuring good water solubility while barely dissolving in low-polarity organic solvents.
This biologically-active substance serves as an important methyl-donor co-factor participating in multiple intracellular metabolic pathways. It is widely used for the synthesis of medicines targeting liver and joint disorders.
Ademetionine Disulfate Tosylate Chemical Properties
| Melting point | >122°C (dec.) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO (Slightly, Heated), Water (Sparingly) |
| form | Solid |
| color | White to off-white |
| Stability: | Hygroscopic; sensitive to moisture, heat, light and alkaline conditions |
| Purity | Commonly ≥98% (HPLC), depending on grade |
| InChI | InChI=1/C15H22N6O5S.C7H8O3S.2H2O4S/c1-27(3-2-7(16)15(24)25)4-8-10(22)11(23)14(26-8)21-6-20-9-12(17)18-5-19-13(9)21;1-6-2-4-7(5-3-6)11(8,9)10;2*1-5(2,3)4/h5-8,10-11,14,22-23H,2-4,16H2,1H3,(H2-,17,18,19,24,25);2-5H,1H3,(H,8,9,10);2*(H2,1,2,3,4)/t7-,8+,10+,11+,14+,27?;;;/s3 |
| InChIKey | XDCFCHNAIMYBAZ-DUXZMFTLNA-N |
| SMILES | S(C1C=CC(C)=CC=1)(O)(=O)=O.S(O)(O)(=O)=O.O[C@@H]1[C@@H]([C@@H](C[S+](C)CC[C@H](N)C(=O)O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.S(O)([O-])(=O)=O |&1:17,18,19,25,31,r| |
| CAS DataBase Reference | 97540-22-2(CAS DataBase Reference) |
| Risk Statements | 36/37/38 |
| Safety Statements | 24/25 |
| HS Code | 2934990002 |
Product Application of Ademetionine Disulfate Tosylate CAS#97540-22-2
Ademetionine disulfate tosylate serves as a stabilized pharmaceutical raw-material that supplies biologically-active ademetionine, an essential methyl-donor co-factor for numerous intracellular metabolic pathways. Apart from liver-protection drug formulation targeting intrahepatic cholestasis and hepatocyte oxidative injury, this compound is applied in the development of preparations for mood-regulation and osteoarthritis-related inflammation relief.
It is also widely used in biochemical laboratory assays for investigating transmethylation mechanisms and enzyme activity. The improved salt-form stability enables it to be processed into injectable or oral dosage-form intermediates, supporting both pilot-scale pharmaceutical production and new-drug pre-clinical research of metabolic-modulating molecules.
