CALAMINE CAS#8011-96-9

Natural Mineral-Derived Ingredient: Calamine is a naturally occurring carbonate mineral ore with a stable composition and is widely recognized for its mineral-based properties.

Fine Uniform Particle Size: Features soft, fine powder texture, good dispersion and easy mixing in lotions, creams and ointment systems.

Soothing and Skin Care Benefits: Calamine provides moisturizing, anti-itching, and soothing effects, making it suitable for applications targeting skin irritation, eczema, and discomfort.

Good Formulation Compatibility: Stable under normal storage conditions, compatible with most common excipients for topical skincare and pharma formulations.

Product Description of CALAMINE CAS#8011-96-9

Calamine is a fine pale pink powder mainly composed of zinc oxide blended with a minor fraction of ferric oxide, complying with pharmacopoeia specifications for pharmaceutical and cosmetic raw materials. It is insoluble in water and ethanol, while dissolving in dilute acids with mild reaction. This mineral powder features soft texture, low impurity levels and stable physical properties under normal storage conditions. 

It is widely recognized as a classic topical protective agent with astringent and soothing effects. It serves as a core ingredient for calamine lotion, ointments and skin care formulations, helping relieve mild skin irritation, redness and itching. Suitable for external dermatological preparations and gentle personal care products, it is processed under controlled production to meet strict heavy metal and microbial limits.

CALAMINE CAS#8011-96-9

CALAMINE Chemical Properties

English NameCALAMINE
English Synonymszinc,iron(3+),oxygen(2-);Calaminelp;CalamineExtraPure;CalamineBp;CalamineUsp;CALAMINE, PHARMA;Cal amine (pharmaceutical preparation);CALAMINE,POWDER,USP
CAS Number8011-96-9
Molecular FormulaFe2O4Zn
Molecular Weight241.0776
AppearanceFine pale pink powder
OdorOdorless
SolubilityInsoluble in water and ethanol; soluble in dilute mineral acids
Bulk DensityApproximately 0.8–1.2 g/cm³
pH (aqueous suspension)7.0–8.5
Loss on drying≤ 2.0%
StabilityStable under normal ambient conditions; avoid humid environment
InChIInChl=1S/2Fe.4O.Zn/q2*+3;4*-2;+2
InChIKeyCPYIZQLXMGRKSW-UHFFFAOYSA-N
SMILES[Zn+2].[Fe+3].[Fe+3].[O-2].[O-2].[O-2].[O-2]
CALAMINE CAS#8011-96-9

Product Application of Calamine CAS#8011-96-9

Calamine is a well-established active ingredient primarily used in dermatological topical preparations. It is widely formulated into calamine lotion, creams and ointments to soothe itchy, irritated skin, relieve mild rashes, insect bites and minor sunburn. Thanks to its astringent and protective properties, it forms a gentle film on the skin surface to reduce exudation and discomfort.

It is also adopted in mild personal care products for sensitive skin, helping calm transient redness. In pharmaceutical manufacturing, it serves as a functional excipient for external formulations. It is only intended for external use and not suitable for oral administration. Its stable performance makes it a preferred raw material for cosmetic and pharma factories producing skin-soothing products.

CALAMINE CAS#8011-96-9

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