Product Description of L-Tryptophan CAS#73-22-3
L-Tryptophan refers to the natural L-type optical isomer of tryptophan. It is a multifunctional substance that can be used for anti-depression related research, nutritional fortification and micronutrient supplementation. It exists naturally as a metabolic component in plants, human bodies and mice, as well as various microorganisms such as Saccharomyces cerevisiae and Escherichia coli.
Classified as a protein-building L-α-amino acid, it belongs to the erythrose 4-phosphate/phosphoenolpyruvate amino acid family. Chemically, it also acts as the conjugate base derived from L-tryptophanium ions.
L-Tryptophan Chemical Properties
| Melting point | 289-290 °C (dec.)(lit.) |
| alpha | -31.1 º (c=1, H20) |
| Boiling point | 342.72°C (rough estimate) |
| density | 1.34 |
| bulk density | 400kg/m3 |
| refractive index | -32 ° (C=1, H2O) |
| storage temp. | 2-8°C |
| solubility | 20% NH3: 0.1 g/mL at 20 °C, clear, colorless |
| form | powder |
| pka | 2.46(at 25℃) |
| color | White to yellow-white |
| PH | 5.5-7.0 (10g/l, H2O, 20℃) |
| Odor | wh. cryst. or cryst. odorless powd., sl. bitter taste |
| biological source | non-animal source |
| Optical Rotation | [α]20/D 31.5±1°, c = 1% in H2O |
| Water Solubility | 11.4 g/L (25 ºC) |
| Merck | 149797 |
| BRN | 86197 |
| Stability: | Stable. Incompatible with strong acids, strong oxidizing agents. |
| InChIKey | QIVBCDIJIAJPQS-VIFPVBQESA-N |
| LogP | 0.704 (est) |
| CAS DataBase Reference | 73-22-3(CAS DataBase Reference) |
| NIST Chemistry Reference | L-Tryptophan(73-22-3) |
| EPA Substance Registry System | L-Tryptophan (73-22-3) |
| Absorption | cut-off at 326nm in 0.5 M HCl at 0.5M |
Safety Information
| Hazard Codes | Xi |
| Risk Statements | 33-40-62-41-37/38-36/37/38-22 |
| Safety Statements | 24/25-36/37/39-36-26 |
| WGK Germany | 2 |
| RTECS | YN6130000 |
| F | 8 |
| TSCA | Yes |
| HS Code | 29339990 |
| Hazardous Substances Data | 73-22-3(Hazardous Substances Data) |
| Toxicity | LD508mmol / kg (rat, intraperitoneal injection). It is safe when used in food (FDA, §172.320, 2000). |
Product Applications of L-Tryptophan CAS#73-22-3
As one indispensable amino acid, L-Tryptophan facilitates the healthy growth of infants and sustains nitrogen equilibrium within adult human bodies. It is widely prepared into natural nutritional-supplement goods and incorporated into formulations meant for easing anxious moods, lifting spirits and improving sleeping quality.
Besides, this amino-acid works as the biochemical starting substance for generating niacin, indole-type alkaloids and serotonin. For laboratory-based investigations, it can also be utilised as a native fluorescent-detection probe to analyse the surrounding micro-environment of tryptophan residues.
